产品货号:
Z38431
中文名称:
Thymidylate Synthase/TYMS抗体
英文名称:
Anti-Thymidylate Synthase/TYMS Antibody (Clone#OTI10F12)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Thymidylate Synthase/TYMS Antibody (Clone#OTI10F12) |
指标别名 | HsT422;Thymidylate synthase;thymidylate synthetase;TMS;TS;TSase;TYMS |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | TYMS |
克隆号 | OTI10F12 |
抗体来源 | Mouse |
抗体类型 | IgG2a |
免疫原 | Full length human recombinant protein of human TYMS (NP_001062) produced in E.coli. |
实际分子量 | 35.5KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor.This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair.The enzyme has been of interest as a target for cancer chemotherapeutic agents.It is considered to be the primary site of action for 5-fluorouracil,5-fluoro-2-prime-deoxyuridine,and some folate analogs.Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.[provided by RefSeq,Jul 2008] |
Uniprot ID | P04818 |
基因名全称 | thymidylate synthetase |
蛋白名全称 | Thymidylate synthase |
推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
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